• Automated segmentation of magnetic resonance bone marrow signal: a feasibility study 

      von Brandis, Elisabeth; Jenssen, Håvard Bjørke; Avenarius, Derk Frederik Matthaus; Bjørnerud, Atle; Flatø, Berit; Tomterstad, Anders; Lilleby, Vibke; Rosendahl, Karen; Sakinis, Tomas; Zadig, Pia Karin Karlsen; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-02)
      Background - Manual assessment of bone marrow signal is time-consuming and requires meticulous standardisation to secure adequate precision of findings.<p> <p>Objective - We examined the feasibility of using deep learning for automated segmentation of bone marrow signal in children and adolescents.<p> <p>Materials and methods - We selected knee images from 95 whole-body MRI examinations of ...
    • A novel magnetic resonance imaging scoring system for active and chronic changes in children and adolescents with juvenile idiopathic arthritis of the hip 

      Tanturri De Horatio, Laura; Shelmerdine, Susan C.; d’Angelo, Paola; Di Paolo, Pier Luigi; Magni-Manzoni, Silvia; Malattia, Clara; Damasio, Maria Beatrice; Tomà, Paolo; Avenarius, Derk Frederik Matthaus; Rosendahl, Karen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-23)
      Abstract Background Hip involvement predicts severe disease in juvenile idiopathic arthritis (JIA) and is accurately assessed by MRI. However, a child-specifc hip MRI scoring system has not been validated.<p> <p>Objective To test the intra- and interobserver agreement of several MRI markers for active and chronic hip changes in children and young adults with JIA and to examine the precision of ...
    • Pediatric whole-body magnetic resonance imaging: comparison of STIR and T2 Dixon sequences in the detection and grading of high signal bone marrow changes 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Müller, Lil-Sofie Ording; Tanturri De Horatio, Laura; Rosendahl, Karen; Avenarius, Derk Frederik Matthaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-26)
      Objectives To compare short time inversion recovery (STIR) and T2 Dixon in the detection and grading of high signal intensity areas in bone marrow on whole-body MRI in healthy children. <p><p>Methods Prospective study, including whole-body 1.5-T MRIs from 77 healthy children. Two experienced radiologists in consensus identifed and graded areas of high bone marrow signal on STIR and T2-weighted (T2W) ...
    • Whole body magnetic resonance imaging in healthy children and adolescents. Bone marrow appearances of the axial skeleton 

      von Brandis, Elisabeth; Zadig, Pia Karin Karlsen; Avenarius, Derk Frederik Matthaus; Flatø, Berit; Knudsen, Per Kristian; Lilleby, Vibke; Nguyen, Bac; Rosendahl, Karen; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-27)
      Objective - To describe the findings of focal high signal on T2 weighted (T2W) images of the bone marrow in the axial skeleton as assessed by whole-body MRI in healthy and asymptomatic children and adolescents.<p> <p>Material and methods - We assessed the bone marrow of the mandible, shoulder girdle, thorax, spine, and pelvis on water-only Dixon T2W sequences as part of a whole-body MRI protocol ...
    • Whole body magnetic resonance imaging in healthy children and adolescents: Bone marrow appearances of the appendicular skeleton 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Flatø, Berit; Müller, Lil-Sofie Ording; Nordal, Ellen Berit; Tanturri De Horatio, Laura; Rosendahl, Karen; Avenarius, Derk Frederik Matthaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-20)
      Objective: To describe the appearances of bone marrow in the appendicular skeleton on fat-suppressed T2- weighted sequences as assessed by whole-body MRI in healthy and asymptomatic children and adolescents.<p> <p>Material and methods: Following ethical approval, we assessed the bone marrow of the extremities on water-only Dixon T2-weighted images as part of a whole-body MRI in 196 healthy and ...
    • Whole-body MRI in children aged 6–18 years. Reliability of identifying and grading high signal intensity changes within bone marrow 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; d’Angelo, Paola; Tanturri de Horatio, Laura; Müller, Lil-Sofie Ording; Rosendahl, Karen; Avenarius, Derk Frederik Matthaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-21)
      Background - Whole-body magnetic resonance imaging (MRI) is increasingly being used in children, however, to date there are no studies addressing the reliability of the findings.<p> <p>Objective - To examine intra- and interobserver reliability of a scoring system for assessment of high signal areas within the bone marrow, as visualized on T2-weighted, fat-saturated images.<p> <p>Materials and ...
    • Whole-body MRI in children and adolescents: Can T2-weighted Dixon fat-only images replace standard T1-weighted images in the assessment of bone marrow? 

      Tanturri De Horatio, Laura; Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Müller, Lil-Sofie Ording; Rosendahl, Karen; Avenarius, Derk Frederik Matthaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-08)
      Objective: When performing whole-body MRI for bone marrow assessment in children, optimizing scan time is crucial. The aim was to compare T2 Dixon fat-only and TSE T1-weighted sequences in the assessment of bone marrow high signal areas seen on T2 Dixon water-only in healthy children and adolescents. <p><p>Materials and methods: Whole-body MRIs from 196 healthy children and adolescents aged 6 to 19 ...